in spite of後面加is還是are

in spite of+名詞、代詞、名詞性從句（賓語從句）。如：He stuck to his own opinion in spite of what I had said.

例句，In spite of his age， he still leads an active life.

儘管年事已高，他依舊過着一種忙碌的生活。

She is still very active， in spite of her advancing years.

她儘管年事漸高，仍然十分活躍。